P53 /
"This volume, 'p53', was developed primarily as a resource for access to key ideas in the field that have developed over the years including how transgenics have been used to study p53, how clinical genetics have identified and studied mutations in p53 found in human cancers, how p53...
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| Online Access: | Electronic book from Springer Complete |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: | Austin, Texas, USA : Landes Bioscience ; New York, New York, USA : Springer Science+Business Media, [2010] Ã2010 |
| Series: | Molecular biology intelligence unit (Unnumbered : 2003)
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| Subjects: |
| Summary: | "This volume, 'p53', was developed primarily as a resource for access to key ideas in the field that have developed over the years including how transgenics have been used to study p53, how clinical genetics have identified and studied mutations in p53 found in human cancers, how p53 can be regulated by post-translational modification, and how key drug targets have been defined, namely MDM2, which has provided fundamental approaches for defining how p53 can be activated with potentially therapeutic effect. The key concepts in the chapters included provide a perspective on key paradigms in the p53 field"--Provided by publisher. |
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| Physical Description: | 1 online resource (189 pages) : illustrations (some color) |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9781441982315 1441982310 |
| Access: | Access limited to authorized users. |